Differences between the Antioxidation Effects of Butylated Hydroxyanisole and Butylated Hydroxytoluene on Acetaminophen - Induced Hepatic Metabolism in Rats
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چکیده
منابع مشابه
Hepatoprotective effect of food preservatives (butylated hydroxyanisole, butylated hydroxytoluene) on carbon tetrachloride-induced hepatotoxicity in rat
Carbon tetrachloride (CCl4), a hepatotoxic agent is widely used to study the toxic mechanisms in experimental animals. This study was carried out to establish the hepatoprotective measures of food preservative antioxidants butylated hydroxyanisole and butylated hydroxytolune (BHA, BHT) when mixed with food towards carbon tetrachloride (CCl4) intoxication (230 mg/ kg b wt/rat/day) in rat. Bioche...
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Both carcinogenic and anticarcinogenic properties have been reported for the synthetic antioxidants butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT). The association between dietary intake of BHA and BHT and stomach cancer risk was investigated in the Netherlands Cohort Study (NLCS) that started in 1986 among 120,852 men and women aged 55 to 69 years. A semi-quantitative food f...
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The modifying effects of antioxidants were examined in a carcinogenesis system after \, V-ililnilvlniinisamiiic treatment. Male F344 rats were given 0.05% V, Vdilnilylnhrosarnmiin their drinking water for 4 wk and then treated with basal diet containing 2% butylated hydroxyanisole (BHA), 1% butylated hydroxytoluene (BHT) with 7 ppm vitamin K, 0.8% ethoxyquin, 5% sodium L-ascorbate, 57. sodium e...
متن کاملEffects of butylated hydroxyanisole on acetaminophen hepatotoxicity and glucuronidation in vivo.
The present study examined the effects of butylated hydroxyanisole (BHA) on acetaminophen-induced hepatotoxicity and metabolism in vivo with emphasis on possible changes in the glucuronidation pathway. Female Swiss-Webster mice received BHA in the diet (1% w/w) for 12 days (600 to 800 mg/kg/day). BHA prevented acetaminophen hepatotoxicity (600 mg/kg, ip), based on serum alanine and aspartate am...
متن کاملEffects of Butylated Hydroxytoluene on Freezability of Ram Spermatozoa
The present study was conducted to investigate the effects of butylated hydroxytoluene (BHT) supplementation on diluted, cooled and frozen-thawed ram spermatozoa. After primary evaluation of collected ejaculates, only semen samples with motility of more than 70% and sperm concentration higher than 3×10 sperm/ml were used for cryopreservation. The selected semen samples were then pooled and dilu...
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ژورنال
عنوان ژورنال: Journal of Oleo Science
سال: 2006
ISSN: 1345-8957,1347-3352
DOI: 10.5650/jos.55.347